cis-3-(tert-Butoxycarbonylamino)cyclobutanecarboxylic acid - Names and Identifiers
cis-3-(tert-Butoxycarbonylamino)cyclobutanecarboxylic acid - Physico-chemical Properties
Molecular Formula | C10H17NO4
|
Molar Mass | 215.25 |
Density | 1.17±0.1 g/cm3(Predicted) |
Boling Point | 368.3±31.0 °C(Predicted) |
pKa | 4.58±0.40(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Irritant |
MDL | MFCD06657680 |
cis-3-(tert-Butoxycarbonylamino)cyclobutanecarboxylic acid - Introduction
3-BOC-aminocyclobutanecarboxylic acid is an organic compound with the chemical name (2S)-2-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylic acid. It has the following properties:
1. Appearance: colorless to yellowish solid.
2. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dimethylformamide.
3. Melting point: about 70-80°C.
3-BOC-aminocyclobutanecarboxylic acid is an important organic synthesis intermediate, which has a wide range of applications in the pharmaceutical field. It can be used to synthesize various amino acids and peptide compounds, such as synthetic drugs and peptide drugs. In addition, it can also be used as a protective group in organic synthesis reactions.
The method for preparing 3-BOC-aminocyclobutanecarboxylic acid is generally carried out through the following steps:
1. Dissolve cyclobutanecarboxylic acid in dimethyl sulfoxide.
2. Add di-tert-butyl carbonate and an active base catalyst, such as triethylamine.
3. React at an appropriate temperature for several hours until the reaction is over.
4. The reaction mixture was worked up and purified to obtain 3-BOC-aminocyclobutanecarboxylic acid product.
Regarding safety information, 3-BOC-aminocyclobutanecarboxylic acid is a chemical that needs to be operated under conditions that comply with relevant laboratory operating safety regulations. Wear appropriate personal protective equipment such as laboratory gloves, goggles and laboratory coats when in use. In addition, avoid contact with skin and eyes, and avoid inhaling its dust or vapor. After use, it should be stored properly and away from ignition and oxidizing agents. In the event of an accident, appropriate first aid measures should be taken immediately and professional advice should be consulted.
Last Update:2024-04-09 20:52:54